Effects on metabolism and cognitive functions by hypnotics induced slow wave sleep modulation in healthy young male volunteers

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Slow wave sleep(deep sleep) is known to be important to maintain glucose tolerance, i. e. to avoid diabetes in future. It is also known that certain hypnotic increases or decreases slow wave sleep. To clear whether hypnotics induced slow wave modulations have equivalent effect on glucose tolerance as that induced by behavior or sleep deprivation, we investigated glucose tolerance in the morning preceded by nighttime hypnotic administration. It was suggested that hypnotic administration improves glucose tolerance. However, relation between slow wave modulation and glucose tolerance was not cleared. We will continue this study to add participants.