Automatic method for cerebral contour extraction and volumetric study on MRI of developing brain.

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We have developed a new automatic method for extracting cerebral contour of developing brain from 3D MR imaging using AFSS(automated fuzzy logic based skull stripping) and fuzzy active surface model(FASM). We also developed better novel method to strip the skull. This method enables us automatic quantitative analysis of infantile brain, which is on the way of developing. Also, it enables us standardization of infantile brain, which is important to know focal brain changes. We also developed several methods(thick rubber model and particle model) for automatic extraction of cerebral sulci and gyri. However, further investigations are needed in this field.