promote liver regeneration after portal vein embolization using platelet administration

使用血小板给药促进门静脉栓塞后的肝再生

• 批准号: 21591594
• 负责人: MURAOKA Noriaki
• 金额: $ 2.83万
• 依托单位: University of Fukui
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21591594/
• 关键词: 放射線; IVR; 肝容積増加; 門脈塞栓術; 血小板; MIB1染色; 2核化肝細胞

To investigate the effect of platelets administration for liver volume increase, portal vein embolization was performed using pig with or without platelets administraion. For volume increase of non-embolized liver, no significant difference was found between the group of administration of platelets and control. There were no significant differences in histopathological investigation of non-embolized liver(count of hepatocyte of two nuclei and MIB1 index).

为了研究血小板给药对肝脏体积增加的影响，使用猪进行门静脉栓塞，有或没有血小板给药。对于未栓塞肝脏的体积增加，血小板给药组与对照组之间无显著差异。未栓塞组的肝组织病理学检查（两核肝细胞计数和MIB1指数）无显著差异。