Reconstruction of skull defect by means of transport distraction osteogenesis with the aid of guided tissue regeneration method.

借助引导组织再生方法，通过运输牵张成骨重建颅骨缺损。

• 批准号: 21592292
• 负责人: HONDA Takayuki
• 金额: $ 2.91万
• 依托单位: Iwate Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592292/
• 关键词: 再生医学; 骨トランスポート法; GTR法; GBR法

This study was aimed to reconstruct a skull defect by means of transport distraction osteogenesis. Based on "guided tissue regeneration method", we planned experimental study using rabbit skull. Transport distraction osteogenesis was performed on rabbit skull and the distraction site was covered with e-PTFE membrane. In our hypothesis, regenerate bone was not disturbed by surrounded soft tissue so that quality of new bone should be better than the regenerate that made by distraction without membrane. However, measurement of regenerate bone was not greater than regenerate made by conventional distraction without membrane.

本研究旨在通过运输牵张成骨技术重建颅骨缺损。本研究在“引导组织再生法”的基础上，对兔颅骨进行了实验研究。在兔颅骨上进行运输牵张成骨，牵张部位覆盖e-PTFE膜。我们假设，再生骨不受周围软组织的干扰，因此，新骨的质量应优于无膜牵张的再生骨。但再生骨的测量值并不大于传统无膜牵张的再生骨。