Morphological analysis of cementogenesis using a newly identified cementoblast specific marker

我们证实了水通道蛋白在牙骨质形成过程中的表达。在脱细胞牙骨质形成过程中，发育中的牙根表面细胞表达水通道蛋白。我们用免疫组织化学方法鉴定这些细胞为牙骨质母细胞。在牙槽骨发育过程中，水通道蛋白在牙周膜-牙槽骨交界处的细胞上有表达。这些细胞显示出与成牙骨质细胞不同的形状，并具有翼状突起。这些结果提示水通道蛋白在牙周组织发育过程中起着重要的作用。

We demonstrated the expression of aquaporin during cementgenesis. Cells on the developing root surface expressed aquaporin in rat molars during acellular cementgenesis. We immuno-histochemicaly identified these cells as cementblasts. The expression of aquaporin was observed on the cells on the interface between periodontal ligament and alveolar bone during alveolar bone development. These cells showed the different shapes from cementoblasts and possessed wing-like projections. These results suggest that aquapolin plays an important role during the development of periodontal tissue.