New Thermal sensory role of Oral epithelia

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The oral cavity is covered by oral epithelia Oral epithelia undergo various stimuli such as temperature or mechanical stimuli. Oral epithelia properly sense those stimuli and then discard toxic or harmful substances and ingest materials necessary for our body. Even though a wider range of temperatures stimulates the oral cavity more than other parts of the body, we do not know the mechanisms of the oral thermal sensory system. We hypothesized that oral epithelia have thermal sensory properties and which then adapt to the oral envimnment We found that thermosensitive transient receptor potential(TRP) channels were functionally expressed in oral epithelia It is suggested that proliferation and epithelial cell cell contact were regulated via channel activity.