The cause and effect relationship between the intractable dermatosis by metal allergy and the metal restoration in the oral cavity.

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The purpose of this study is the elucidation of a pathogenic mechanism of metal allergy and establishment of a new inspection method, when the sweat from subject who had intractable dermatosis by dental metal allergy is analyzed.The hand was soaked for 10 minutes into 42℃warm water, and sweat was extracted. Qualitative analysis of the sample was conducted with Inductively coupled plasma optical emission spectrometry equipment.When conditions were made severe, it became impossible to detect, although 16 kinds of metallic elements have detected by the simple examination. It is necessary to raise adjustment of the sample, or the detection limit of analysis equipment.