The cause and effect relationship between the intractable dermatosis by metal allergy and the metal restoration in the oral cavity.

金属过敏引起的顽固性皮肤病与口腔金属修复的因果关系。

• 批准号: 21592460
• 负责人: TERANO Motohiro
• 金额: $ 3万
• 依托单位: Nagasaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592460/
• 关键词: 歯学; アレルギー; 金属; 汗

The purpose of this study is the elucidation of a pathogenic mechanism of metal allergy and establishment of a new inspection method, when the sweat from subject who had intractable dermatosis by dental metal allergy is analyzed.The hand was soaked for 10 minutes into 42℃warm water, and sweat was extracted. Qualitative analysis of the sample was conducted with Inductively coupled plasma optical emission spectrometry equipment.When conditions were made severe, it became impossible to detect, although 16 kinds of metallic elements have detected by the simple examination. It is necessary to raise adjustment of the sample, or the detection limit of analysis equipment.

本研究的目的是通过分析因牙科金属过敏而患有顽固性皮肤病的受试者的汗液，以阐明金属过敏的致病机制并建立新的检查方法。将手在42℃温水中浸泡10分钟，并提取汗液。使用电感耦合等离子体发射光谱仪对样品进行定性分析。虽然通过简单的检查检测出了16种金属元素，但当条件恶劣时，就无法检测到。需要提高样品的调整，或者分析设备的检测限。

项目成果

歯科用金属アレルギーを疑われた掌蹠膿疱症患者の治療成績

疑似牙齿金属过敏的掌跖脓疱病患者的治疗结果

• 发表时间: 2009
• 作者: 七田俊晴;佐藤裕二;北川昇;寺野元博
• 通讯作者: 寺野元博