课题基金 / 基金详情

Molecular biological study on the mechanism of alveolar bone metabolism through the toll-like receptor 5

Molecular biological study on the mechanism of alveolar bone metabolism through the toll-like receptor 5
Toll样受体5影响牙槽骨代谢机制的分子生物学研究
批准号:
21592639
负责人:
NAKAMURA Kimiya
金额:
$2.58万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

项目摘要

项目成果

NAKAMURA Kimiya的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Flagellin, the ligand of Toll like receptor 5, markedly increased the expression of MCP-1 which is one of the CC chemokine, in a dose-dependent manner on osteoblastic MC3T3-E1 cells. In addition, flagellin was significantly suppressed the OPG mRNA expression. Furthermore, anti-MCP-1 antibody was further down-regulated the flagellin-suppressed OPG mRNA expression. These results indicate that osteoblasts are involved in host defense as well as bone metabolism.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
骨芽細胞様MC3T3-E1細胞におけるTLR5リガンドによるMCP-1の発現誘導
TLR5 配体在成骨细胞样 MC3T3-E1 细胞中诱导 MCP-1 表达
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Matsumura Y, Mitani A, Suga T, Kamiya Y, Kikuchi T, Tanaka S, Aino M, Noguchi T, 中村公也,竹原順次,三宅亮,兼平孝]
通讯作者: 中村公也,竹原順次,三宅亮,兼平孝
Flagellin induces MCP-1 in mouse osteoblastic cells
鞭毛蛋白在小鼠成骨细胞中诱导 MCP-1
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [Kimiya Nakamura, Yoshiaki Deyama, Yoshitaka Yoshimura, Kuniaki Suzuki]
通讯作者: Kuniaki Suzuki
Toll like receptor 5 ligand induces monocyte chemoattractant protein-1 in mouse osteoblastic cells
Toll样受体5配体诱导小鼠成骨细胞中的单核细胞趋化蛋白-1
DOI: 10.2220/biomedres.33.39
发表时间: 2012
期刊: Biomedical Research
影响因子: --
作者: [Nakamura K, Deyama Y, Yoshimura Y, Suzuki K, Morita M]
通讯作者: Morita M
Relation between progress of periodontal disease and toll-like receptor ligand
  • 批准号:
    19592400
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 资助金额:
    $2.33万
  • 财政年份:
    2007
  • 负责人:
    NAKAMURA Kimiya
  • 依托单位:
海外基金