Possibility of the oral microorganism control in the elderly by a gel-entrapped catechin

凝胶包埋儿茶素（GEC）对口腔微生物的体外抑菌实验均发现了对纳氏放线菌、变形链球菌、白色念珠菌和牙周病菌的抑菌带。相比之下，对在本地口腔菌群中起重要作用的口腔链球菌没有抑制作用。GEC的抑菌活性与过氧化氢有关。另一方面，在体内实验中，应用GEC观察到相同的抑菌活性。这些结果表明，GEC可用于老年人的口腔护理。

Microbial inhibition zones against oral microorganisms using gel-entrapped catechin(GEC) were found for all of the strains of Actinomyces naeslundii, Streptococcus mutans, Candida albicans and periodontopathic bacteria in vitro assay. By contrast, no inhibitory effect was observed for oral streptococci which play an important role in indigenous oral flora. The anti-microbial activity of GEC is related with hydrogen peroxide. On the other hand, in vivo assay, same anti-microbial activity was observed by the application of GEC.These results suggest that GEC could be useful for oral care in the elderly.