Effects of nicotine on the signal transduction in osteoclast precursors
Effects of nicotine on the signal transduction in osteoclast precursors
批准号:
21792132
负责人:
TANAKA Hideki
金额:
$1.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
尼古丁诱导破骨细胞前体CAⅱ、炎性细胞因子和PGE2的表达。在COX-2抑制剂存在的情况下,尼古丁不诱导CA II表达。这些结果表明,PGE2以自分泌方式诱导CA II的表达。
英文摘要
Nicotine induces the expression of CA II, inflammatory cytokines and PGE2 in osteoclast precursors. In the presence of COX-2 inhibitor , nicotine did not induce CA II expression. These results suggest that PGE2 play a role in the induction of CA II expression by autocrine manner.
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DOI:
10.1016/j.biochi.2009.12.011
发表时间:
2010-04-01
期刊:
BIOCHIMIE
影响因子:
3.9
作者:
[Kitami, Satoshi, Tanaka, Hideki, Maeno, Masao]
通讯作者:
Maeno, Masao
酪酸は骨芽細胞の分化を抑制しPGE_2産生を促進する
丁酸盐抑制成骨细胞分化并促进 PGE_2 产生
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[飯田隆文, 田中秀樹, 川戸貴行, 前野正夫]
通讯作者:
前野正夫
ホームページ等。
主页等
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
酪酸は骨芽細胞のCOX-1およびCOX-2発現増加を介してPGE2産生を促進する.
丁酸盐通过增加成骨细胞中 COX-1 和 COX-2 的表达来促进 PGE2 的产生。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[飯田隆文, 田中秀樹, 上遠野(谷)朋子, 桑原亜貴子, 川戸貴行, 田邊奈津子, 前野正夫, 川口隆彦]
通讯作者:
川口隆彦
Butyric acid induces Coxs and PGE2 production in ROS17/2.8 cells. 1725
丁酸诱导 ROS17/2.8 细胞中 Coxs 和 PGE2 的产生。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Iida T, Kawato T, Tanaka H, Katono-Tani T, Kuwabara A, Tanabe N, Kawaguchi T, Maeno M]
通讯作者:
Maeno M
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Transnationalization and demutualization of agricultural cooperatives under EU single market, and their governance structure
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Modeling of One-dimensional Quantum Hydrogen by Path Integral Formalism
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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Experimental study on seasonal adaptable sustainable house integrated with design-structure- household equipment
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Hydration and transport phenomena of ions in nano pores and ion channels
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批准号:21245006
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$17.39万
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Phase Behaviors of Quantum Fluids in Pores - Modeling of Condensation and Solidification Behaviors
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批准号:19750113
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依托单位:
Fluctuation and Chemical Reaction in Low-dimensional Condensed Phase
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批准号:18066011
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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Structure and dynamics of water and silicon in carbon nanotube
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批准号:15201021
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Comprehensive research on the formation and development of support measures for patients with mental disorders in the Kyushu Region
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Transformation of consumer co-operatives and their rolls for community
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批准号:14597004
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Two kinds of potential surfaces for supercooled water and percolation transition
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Pathogenesis of the congenital anormaly in the upper extremity
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依托单位:
Theoretical Study on a phase transition between low temperature metastable water phases
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批准号:08640646
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依托单位:
Thermodynamic Stobility and Melting Mechanism of Clathrate Hydrate
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批准号:05640567
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.83万
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负责人:TANAKA Hideki
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依托单位:
海外基金