Neuroimaging and Neuropsychological studies on neural basis of episodic memory

不同脑区在情景记忆的编码和提取中的功能已被深入研究，但每个脑区的具体贡献尚未阐明。本研究的目的是确定支持事件记忆本身，时间背景记忆，空间背景记忆和源记忆的神经网络。为此，我们采用了神经影像学和神经心理学研究。结果表明：（1）在情景记忆提取过程中，前额叶活动对内侧颞叶活动的影响;（2）内侧颞叶在源记忆提取中的关键作用;（3）内侧颞叶内各亚区在情景记忆提取中的不同作用。

The functions of various brain areas on the encoding and retrieval of episodic memory have been studied intensely, yet the specific contribution of each brain area has not been elucidated. The purpose of the present study was to identify neural networks that support event memory itself, temporal context memory, spatial context memory, and source memory. For this purpose, we employed both neuroimaging and neuropsychological studies. The results showed (1)the influence of prefrontal activity on medial temporal lobe activity during the retrieval of episodic memory,(2)the crucial role of the medial temporal lobe in the retrieval of source memory, and (3)the differential roles of subregions within the medial temporal lobe in episodic memory.