Development of virus filter using electret apatite complex adsorbent

使用驻极体磷灰石复合吸附剂开发病毒过滤器

• 批准号: 21300184
• 负责人: IKOMA Toshiyuki
• 金额: $ 11.81万
• 依托单位: Tokyo Institute of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21300184/
• 关键词: ナノバイオ材料; ウイルス不活化; 有機無機複合; 静電気力

Hydroxyapatite nanocrystals(HAp) with the property of electrical attraction to virus was developed by applying pure HAp at a constant voltage, called as electret HAp(E-HAp). The adsorption properties of fibroblast and baculovirus to pure HAp and E-HAp have no difference ; however, the amount of adsorbed baculovirus to pure HAp was three times higher than that of polystyrene. Inactivation of the adsorbed virus should be needed for the further immobilization of a virus inactivation agency.

通过在恒定电压下施加纯羟基磷灰石纳米晶（HAp），制备出对病毒具有电吸引作用的驻极体HAp（E-HAp）。成纤维细胞和杆状病毒对纯HAp和E-HAp的吸附性能没有差异，但杆状病毒对纯HAp的吸附量是聚苯乙烯的3倍。为了进一步固定病毒灭活剂，需要灭活吸附的病毒。

项目成果

Efficient synthesis of Eu(III)-containing nanoporous silicas

• DOI: 10.1016/j.matlet.2011.04.011
• 发表时间: 2011-07
• 期刊: Materials Letters
• 影响因子: 3
• 作者: M. Tagaya;T. Ikoma;T. Yoshioka;S. Motozuka;Fujio Minami;J. Tanaka

Reusable hydroxyapatite nanocrystal sensors for protein adsorption

• DOI: 10.1088/1468-6996/11/4/045002
• 发表时间: 2010-02
• 期刊: Science and Technology of Advanced Materials
• 影响因子: 5.5
• 作者: M. Tagaya;T. Ikoma;N. Hanagata;D. Chakarov;B. Kasemo;J. Tanaka

ハイドロキシアパタイト

羟基磷灰石

• 发表时间: 2011
• 期刊: 骨粗鬆症治療
• 作者: 早乙女進一;生駒俊之
• 通讯作者: 生駒俊之

Interfacial Serum Protein Effect on Biological Apatite Growth

• DOI: 10.1021/jp208104z
• 发表时间: 2011-10
• 期刊: Journal of Physical Chemistry C
• 影响因子: 3.7
• 作者: M. Tagaya;T. Ikoma;M. Takeguchi;N. Hanagata;J. Tanaka

Initial adhesion behavior of fibroblasts onto hydroxyapatite nano-crystals

成纤维细胞在羟基磷灰石纳米晶上的初始粘附行为

• 发表时间: 2011
• 期刊: Bioceramics Development and Applications
• 作者: Tagaya M;Ikoma T;Takemura T;Migita S;Okuda M;Yoshioka T;Hanagata N;Tanaka J
• 通讯作者: Tanaka J