Develo pments of the target cooling and dosimetry systems for the use of the accelerator boron neutron capture therapy

用于加速器硼中子俘获疗法的靶标冷却和剂量测定系统的开发

• 批准号: 21310039
• 负责人: MASAHARU Hoshi
• 金额: $ 11.9万
• 依托单位: Hiroshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21310039/
• 关键词: 放射線; BNCT; 加速器; 中性子; リチウムターゲット; 線量測定; 冷却システム; Liターゲット; 中性子線量; ホウ素; 線量評価

New target system for the accelerator boron neutron capture therapy by using water cooling system was developed. The target was tested 6 times using the 3MeV proton beam of the accelerator in National Institute for Radiological Sciences with the same power per unit area and was verified to have enough ability to keep the temperature below about 100 degrees. From these results we can manufacture an actual target system. For the dosimetry system we used new plastic including boron and made verified the possibility of the new chamber system to measure necessary neutrons for boron neutron capture therapy system.

研制了一种用于加速器硼中子俘获治疗的新型水冷靶系统。利用国立放射科学研究所加速器的3MeV质子束以相同的单位面积功率对靶进行了6次测试，并验证了靶具有足够的能力将温度保持在约100度以下。根据这些结果，我们可以制造实际的目标系统。在剂量测量系统中，我们采用了新的含硼塑料，并验证了新的电离室系统测量硼中子俘获治疗系统所需中子的可能性。

项目成果

Genome-Wide Expression Changes in Saccharomyces cerevisiae in Response to High-LET Ionizing Radiation

• DOI: 10.1007/s12010-009-8825-3
• 发表时间: 2010-10-01
• 期刊: APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
• 影响因子: 3
• 作者: Mizukami-Murata, Satomi;Iwahashi, Hitoshi;Hoshi, Masaharu
• 通讯作者: Hoshi, Masaharu

Development of monitoring method of spatial neutron distribution in neutrons-gamma rays mixed field using imaging plate for NCT-Depression of the field

中子-伽马射线混合场空间中子分布NCT-凹陷成像板监测方法的发展

• 发表时间: 2011
• 期刊: Applied Radiation and Isotopes
• 影响因子: 1.6
• 作者: Tanaka;K.
• 通讯作者: K.

Development of monitoring method of spatial neutron distribution in neutrons-gamma rays mixed field using imaging plate

成像板中子-伽马射线混合场空间中子分布监测方法的研制

• 发表时间: 2010
• 期刊: Challenges in Neutron Capture Therapy (Proc.of the 14th International Congress on Neutron Capture Therapy)
• 作者: Tanaka;K.
• 通讯作者: K.

加速器硼素中性子捕捉療法の混合場における線量評価

加速器硼中子俘获治疗混合场剂量评估

• 发表时间: 2010
• 作者: 中尾稔;鬼塚昌彦;馬場大海;深堀麻衣;田中憲一;星正治;佐々木雅之
• 通讯作者: 佐々木雅之

Measurements of neutron distribution inneutrons-gamma rays mixed field usingimaging plate for neutron capturetherapy

中子俘获治疗成像板测量中子-伽马射线混合场中子分布

• 发表时间: 2010
• 期刊: Appl. Radiat. Isot
• 作者: K. Tanaka;S. Endo;M. Hoshi
• 通讯作者: M. Hoshi