Study of Bisphenol A effect on neonatal mouse using genetically modified mouse
Study of Bisphenol A effect on neonatal mouse using genetically modified mouse
批准号:
21310047
负责人:
WATANABE Hajime
金额:
$11.81万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
It has been known that neonatal exposure of Bisphenol A cause adverse effects on mice. Especially effect on nervous stem is one of the great concerns. In this study, I made transgenic mice expressing a marker gene under the control of regulatory region of estrogen receptor alpha and examined the effect of Bisphenol A. In addition, I also examined the effect of Bisphenol A from epigenetic point of view by immunoprecipitation of methylated genome DNA.
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Epigenetic effect of endocrine disruptors
内分泌干扰物的表观遗传效应
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Tanaka S, Miyamoto K, Noda H, Sato R, 高村ゆかり, 今岡進, Hajime Watanabe]
通讯作者:
Hajime Watanabe
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Toyota, K., Kato, Y., Miyagawa, S., Ogino, Y., Kobayashi, K., Oda, S., Watanabe, H. Tatarazako, S., & Iguchi, T.]
通讯作者:
T.
DOI:
10.1016/j.ygeno.2009.12.005
发表时间:
2010-03-01
期刊:
GENOMICS
影响因子:
4.4
作者:
[Kato, Yasuhiko, Kobayashi, Kaoru, Iguchi, Taisen]
通讯作者:
Iguchi, Taisen
DOI:
10.1095/biolreprod.108.070599
发表时间:
2009-11-01
期刊:
BIOLOGY OF REPRODUCTION
影响因子:
3.6
作者:
[Kim, Hannah, Nakajima, Tadaaki, Sato, Tomomi]
通讯作者:
Sato, Tomomi
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[橋本翔子, 佐々木淑絵, 工藤智弘, 今岡進, 渡邉肇]
通讯作者:
渡邉肇
共 33 条
Abscisic Acid and Acceleration of Midstem Elongation in High-Temperature Moisture Treatment-Application and Development for Direct Seeding of Rice-
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批准号:17K07619
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2017
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负责人:WATANABE Hajime
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依托单位:
Evaluation of environmental chemical effects on genome and gene expression
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批准号:15310043
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.11万
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财政年份:2003
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负责人:WATANABE Hajime
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依托单位:
Molecular analysis of novel targets of endocrine disrupters
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批准号:13833010
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.62万
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财政年份:2001
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负责人:WATANABE Hajime
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依托单位:
Regulatory Mechanisms by Appetite-Regulating Peptides of the Neuroendocrine System
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批准号:12671072
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.79万
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财政年份:2000
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负责人:WATANABE Hajime
-
依托单位:
海外基金