Molecular mechanism of signal transduction by reactive oxygen species
Molecular mechanism of signal transduction by reactive oxygen species
批准号:
21390097
负责人:
AKAIKE Takaaki
金额:
$11.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
8-Nitro-cGMP通过蛋白质S-鸟苷酸化参与活性氧介导的信号传导。在这里,我们确定了几个特定的S-鸟苷酸化蛋白(e。例如,在一个实施例中,H-Ras等)发生在细胞中并参与各种细胞信号功能。我们还发现,内源性产生的硫化氢调节细胞中的蛋白质S-鸟苷酸化。
英文摘要
8-Nitro-cGMP is involved in reactive oxygen species-mediated signaling via protein S-guanylation. Here we identified several particular S-guanylated proteins(e. g., H-Ras etc.) occurring in cells and their involvement in various cellular signaling functions. We also revealed that endogenously produced hydrogen sulfide regulates protein S-guanylation in cells.
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新出现的传染病致病菌——胃螺杆菌
DOI:
--
发表时间:
2010
期刊:
日本医事新報
影响因子:
--
作者:
[河村好章, 赤池孝章]
通讯作者:
赤池孝章
Cellular signaling mediated by nitrated cyclic nucleotides
硝化环核苷酸介导的细胞信号传导
DOI:
--
发表时间:
2010
期刊:
Nitric Oxide (in press)
影响因子:
--
作者:
[Akaike T., et al]
通讯作者:
et al
核酸分子の化学修飾による活性酸素シグナルのケミカルセンシング
通过核酸分子的化学修饰对活性氧信号进行化学传感
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[澤智裕, 他]
通讯作者:
他
Detection of protein-bound 3-nitrotyrosine in plasma from pediatric patients with fulminant ARDS and avian influenza infection
暴发性ARDS合并禽流感感染儿科患者血浆中蛋白质结合3-硝基酪氨酸的检测
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Okamoto T., et al]
通讯作者:
et al
A New Paradigm for Antimicrobial Host Defense Mediated by NO and ROS : A Critical Role of Nitrated Nucleotides
NO 和 ROS 介导的抗菌宿主防御的新范例:硝化核苷酸的关键作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[阿南勝宏, 大上直秀, 坂本直也, 林哲太郎, 仙谷和弘, 浦岡直礼, HtooZarniOo, 内藤寛, 坂根潤一, 後藤景介, 野口剛, 安井弥, 赤池孝章]
通讯作者:
赤池孝章
共 99 条
Study of the mechanism of biosynthesis of polysulfurated proteins coupled with translation
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批准号:16K15208
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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财政年份:2016
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Novel signaling pathway of bacterial stress responses and host defense via autophagy
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Mechanism of intracellular formation of cysteine polysulfide and reactive oxygen species signaling
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批准号:25253020
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.79万
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Regulation mechanism by hydrogen sulfide anion of electrophilesignaling
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批准号:23651239
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
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财政年份:2011
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负责人:AKAIKE Takaaki
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依托单位:
Molecular regulatory mechanisms of NO analyzed by using nitronyl nitroxide
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批准号:15087207
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$18.43万
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财政年份:2003
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负责人:AKAIKE Takaaki
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依托单位:
Research on a novel mechanism for oxidative stress mediated by NO-induced nucleic acid nitration.
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批准号:15390107
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$2.69万
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负责人:AKAIKE Takaaki
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依托单位:
Development of analysis for all biologically relevant derivatives of NO
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资助金额:$3.01万
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财政年份:2000
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负责人:AKAIKE Takaaki
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依托单位:
Research on microbial mutation and evolution involving oxidative stress
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批准号:12470038
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资助金额:$6.59万
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Molecular Mechanisms of Redox-Regulation in Viral Pathogenesis
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财政年份:1997
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依托单位:
Viral Pathogenesis and Regulation Mechanism of Free Radicals in Host Responses : Role of Nitric Oxide
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批准号:07670347
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资助金额:$1.47万
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财政年份:1995
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负责人:AKAIKE Takaaki
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依托单位:
Involvement of virus infection in the pathogenesis of pulmonary fibrosis
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批准号:04670472
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资助金额:$1.34万
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财政年份:1992
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负责人:AKAIKE Takaaki
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依托单位:
海外基金