Comprehensive analysis of Bordetella type III effectors
Comprehensive analysis of Bordetella type III effectors
批准号:
21390133
负责人:
ABE Akio
金额:
$11.4万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011
中文摘要
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英文摘要
Bordetella species including Bordetella pertussis deliver effectors into host cells via a type III secretion system(T3SS). Effector-host factor interaction alters host physiological conditions, leading to disease process. In this study, we identified and analyzed new effector(designated BspR) in Bordetella bronchiseptica. BspR effector was translocated into the nucleus, and then interacted with hnRNP H. Interestingly, BspR was a global transcriptional regulator for T3SS and other virulence factors in bacterial cytosol.
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EspJ effector in enterohemorrhagic E. coli translocates into host mitochondria via an atypical mitochondrial targeting signal
肠出血性大肠杆菌中的 EspJ 效应子通过非典型线粒体靶向信号易位到宿主线粒体中
DOI:
10.1111/j.1348-0421.2010.00218.x
发表时间:
2010
期刊:
Microbiology and Immunology
影响因子:
2.6
作者:
[Jun Kurushima, Takeshi Nagai, Kanna Nagamatsu, Akio Abe]
通讯作者:
Akio Abe
感染現象その理解の深化から疾患制御への展望:細菌の病原因子分泌機構の新展開
加深对感染现象的认识对疾病控制的展望:细菌毒力因子分泌机制的新进展
DOI:
--
发表时间:
2009
期刊:
蛋白質核酸酵素
影响因子:
--
作者:
[Khodoun, M., Strait, R., Orekov, T., Hogan, S., Karasuyama, H., Herbert, D. R., Kohl, J. and Finkelman, F. D., 阿部章夫]
通讯作者:
阿部章夫
特集 感染症の現代的課題 : 細菌のエフェクター輸送システムはどれだけわかっているのか
专题:传染病的现代问题:我们对细菌效应器运输系统了解多少?
DOI:
--
发表时间:
2009
期刊:
生体の科学 60
影响因子:
--
作者:
[成田浩司, 中根明夫, ら, 阿部章夫]
通讯作者:
阿部章夫
Bordetella immune evasion by type III effector
博德特氏菌通过 III 型效应子逃避免疫
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ugajin, T., H.Shida, Akio Abe]
通讯作者:
Akio Abe
Bordetellaimmune evasion by type III effectors
III 型效应器的博德特莱免疫逃避
DOI:
--
发表时间:
2013
期刊:
影响因子:
--
作者:
[Uchiyama, J., Sakaguchi, Y., Takemura-Uchiyama, I., Kato, S., Satoh, M., Ujihara, T., Daibata, M., Matsuzaki, S, 桑江朝臣]
通讯作者:
桑江朝臣
共 20 条
Dual effector BspR that functions in Bordetella and host cells
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批准号:25670215
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:ABE Akio
-
依托单位:
Directing of decdritic cells by Bordetella type III effectors
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批准号:24390108
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.48万
-
财政年份:2012
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负责人:ABE Akio
-
依托单位:
A guidance and control system design for reliability improvement of the next space transportation system
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批准号:20760549
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.5万
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财政年份:2008
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负责人:ABE Akio
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依托单位:
Comprehensive analyses of the type III effectors in pathogenic Escherichia coli
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批准号:18390136
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.87万
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财政年份:2006
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负责人:ABE Akio
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依托单位:
Functional analyses of the type III effectors in pathogenic E.coli
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批准号:16590370
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.24万
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财政年份:2004
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负责人:ABE Akio
-
依托单位:
海外基金