Smooth Transition to and Implementation of Palliative Care : Issues in Clinical Practice Guidelines and QOL Assessment

对癌症临床实践指南起草者和姑息治疗临床医生的访谈，以及对其他国家临床实践指南的内容分析，揭示了以下有关过渡到姑息治疗和实施姑息治疗的问题：获取姑息治疗的证据，弥合信息差距，姑息治疗描述的数量和作者特征，并在起草治疗指南时明确显示共识。根据一项全国性的调查，对生活质量的认识大约为20%。我们验证了EORTC QLQ-C15-PAL（姑息治疗患者的QOL评估问卷）的日语版，并将其用于多中心前瞻性研究，证明了临床环境中姑息治疗的QOL评分的最小重要差异（MID）。

Interviews with drafters of clinical practice guidelines for cancer and clinicians involved in palliative care, as well as content analysis of clinical practice guidelines from other countries, revealed the following issues regarding the transition to and implementation of palliative care : obtaining evidence for palliative care, bridging the information gap, the volume of palliative care descriptions and author characteristics, and a clear display of consensus when drafting treatment guidelines. Based on a nationwide survey, awareness of QOL stood at roughly 20%. We verified the Japanese-language edition of the EORTC QLQ-C15-PAL(a QOL assessment questionnaire for palliative care patients), and used it in a multicenter prospective study and demonstrated the minimally important difference(MID) of QOL scores for palliative care in the clinical setting.