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Understanding the pathogenesis of severe airway diseases by large cohort studies

Understanding the pathogenesis of severe airway diseases by large cohort studies
通过大型队列研究了解严重气道疾病的发病机制
批准号:
21390253
负责人:
NISHIMURA Masaharu
金额:
$11.65万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2011

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项目成果

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中文摘要
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英文摘要
The rate of annual change in post-bronchodilator FEV1 is highly variable over a period of 5 years among patients with COPD who receive appropriate therapy. Emphysema severity, which varies substantially even for the same spirometric stage, is independently associated with a rapid annual decline in FEV1. The presence of sustainers, who can maintain pulmonary function, warrants specific attention together with rapid decliners in clinical practice.
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会议论文
Beta2-adrenergic receptor polymorphisms as a determinant of preferential bronchodilator responses to β2-agonist and anticholinergic agents in Japanese patients with chronic obstructive pulmonary disease
β2-肾上腺素能受体多态性是日本慢性阻塞性肺病患者对β2-激动剂和抗胆碱能药物优先支气管扩张剂反应的决定因素
DOI: --
发表时间: 2011
期刊: Pharmacogenet Genomics
影响因子: --
作者: [Y Matsumoto, 他, Yasunobu Uchijima, Konno S]
通讯作者: Konno S
気管支喘息、COPDにおける気管支拡張薬に対する反応
支气管哮喘和慢性阻塞性肺病对支气管扩张剂的反应
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [今野哲]
通讯作者: 今野哲
Predictors of Exacerbation in Japanese Patients with Chronic Obstructive Pulmonary Disease
日本慢性阻塞性肺疾病患者病情加重的预测因素
DOI: --
发表时间: 2011
期刊:
影响因子: --
作者: [Yano Y, Hoshide S, Shimizu M, Eguchi K, Ishikawa J, Ishikawa S, Shimada K, Kario K., Makita H]
通讯作者: Makita H
Relationship between improved airflow limitation and changes in airway caliber induced by inhaled anticholinergic in chronic obstructive pulmonary disease
慢性阻塞性肺疾病患者吸入抗胆碱能药物引起的气流受限改善与气道口径变化的关系
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Li Y, Saito Y, Kuwahara K, Rong X, Kishimoto I, Harada M, Adachi Y, Nakanishi M, Kinoshita H, Horiuchi M, Murray M, Nakao K, 藤澤興, 山下潤, Hasegawa M]
通讯作者: Hasegawa M
23
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