Purinergic circuit formation at the critical period in the mouse retina

视觉系统的回路形成发生在关键期之前，对视觉体验没有任何可塑性改变。由于P2 X2-嘌呤受体回路的形成发生在关键期，我们研究了P2 X2-嘌呤受体回路的形成是否对小鼠视网膜的视觉体验表现出可塑性变化。我们发现P2 X2-嘌呤受体的回路形成对视觉体验没有任何可塑性变化，表明存在内在程序化过程。

Circuit formation of visual system occurs before the critical period and did not show any plastic change to visual experience. Since circuit formation of P2X2-purinoceptor occurs in the critical period, we examined whether the circuit formation of P2X2-purinoceptor shows plastic change to visual experience in the mouse retina. We found that the circuit formation of P2X2-purinoceptors did not show any plastic change to visual experience, suggesting the presence of intrinsically programmed process.