The neural substrate of the plastic change in tactile stimulation.

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We examined an fMRI study to clarify the plastic change of neural substrate in long term training. When participants performed tactile discrimination of experimental stimuli, the V1 were activated in the well-trained subjects. In the control (stimuli naive) subjects, the V1 was not activated. Now we are analyzing the obtained data to reveal the mechanisms and difference of neural substrate between experimental groups about the connectivity of several brain regions, the volumes of brain areas and the neuronal fiber tract.