Crosstalk between the local temperature change inside single living cells and the cellular functions

点击翻译按钮获取中文摘要

The purpose of this study is to clarify the relationship between the temperature and the functions of the brain and the heart in which the [Ca^<2+>] strongly coupled with their function in the microscopic view point. We first focused on clarifying the thermal properties of single living cells. Then the effect of the local temperature gradient was studied with the use of dividing single HeLa cells. Furthermore, the response of the single motile cells to the local temperature gradient and the heat pulse was analyzed. In the meantime, the research was expanded to the studies to elucidate the mechanism of the oscillatory movement of the cardiac cell.