Single-molecule fluorescence photoswitching based on the photochromic conformational changes

基于光致变色构象变化的单分子荧光光开关

• 批准号: 21750149
• 负责人: FUKAMINATO Tsuyoshi
• 金额: $ 2.75万
• 依托单位: Hokkaido University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21750149/
• 关键词: フォトクロミズム; 蛍光; 単一分子; 非破壊読み出し; 幾何構造

Some diarylethene derivatives, which introduce a fluorescent unit at the reactive carbon of diarylethenes were synthesized and studied its fluorescence photoswitching properties. In these studies, an unexpected photoreaction, in which the photocyclization reaction of the photoswitching unit proceeds with non-absorbing wavelength light, was accidently found. From several experiments, it is suggested that the unexpected reaction proceeds from the triplet-state of diarylethene unit. This result was extended to the synthesis of a novel single-molecular fluorescent photoswitching molecule with the non-destructive readout capability. The fluorescence and photochromic performances of this molecule allow us to achieve the fluorescence photoswitching with non-destructive readout in the solution as well as even at the single-molecule level.

合成了在二芳基乙烯活性碳上引入荧光单元的二芳基乙烯衍生物，并研究了其荧光光开关性能。在这些研究中，意外地发现了一个意想不到的光反应，其中光开关单元的光环化反应是在非吸收波长的光下进行的，从几个实验来看，该意想不到的反应是由二芳基乙烯单元的三线态进行的。这一结果被扩展到一个新的单分子荧光光开关分子的非破坏性读出能力的合成。该分子的荧光和光致变色性能使我们能够在溶液中甚至在单分子水平上实现具有非破坏性读出的荧光光开关。

项目成果

Photochromism of a diarylethene derivative in aqueous solution capping with a water-soluble nano-cavitand

• DOI: 10.1016/j.jphotochem.2009.03.010
• 发表时间: 2009-09-05
• 期刊: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
• 影响因子: 4.3
• 作者: Saitoh, Masashi;Fukaminato, Tuyoshi;Irie, Masahiro
• 通讯作者: Irie, Masahiro

Fluorescence Photo-switching Based on Intra-molecular Electron Transfer of Diarylethene-perylenebisimide Dyad

基于二芳基乙烯-苝双酰亚胺二元体分子内电子转移的荧光光开关

• 发表时间: 2010
• 作者: Ohki Sato;Makoto Sato;Hiroshi Sugimoto;Takaaki Kuramochi;Takashi Shirahata;Kazuko Takahashi;T.Fukaminato
• 通讯作者: T.Fukaminato

Single-Molecule Fluorescence Photoswitching of a Diarylethene-Perylenebisimide Dyad: Non-destructive Fluorescence Readout

• DOI: 10.1021/ja110686t
• 发表时间: 2011-04-06
• 期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
• 影响因子: 15
• 作者: Fukaminato, Tuyoshi;Doi, Takao;Irie, Masahiro
• 通讯作者: Irie, Masahiro

Fluorescence photoswitching of a diarylethene-perylenebisimide dyad based on intramolecular electron transfer

• DOI: 10.1039/b9pp00131j
• 发表时间: 2010-01-01
• 期刊: PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
• 影响因子: 3.1
• 作者: Fukaminato, Tuyoshi;Tanaka, Masaaki;Irie, Masahiro
• 通讯作者: Irie, Masahiro

単一分子蛍光計測で探るキラリティーの本質

使用单分子荧光测量探索手性的本质

• 发表时间: 2011
• 作者: S.Takemoto;H.Morita;K.Karitani;H.Fujiwara;H.Matsuaka;深港豪
• 通讯作者: 深港豪