Optimization of Drug Movement in Tape for Percutaneous Absorption on Electrical Control

为了研究用于经皮吸收的带中的药物的电控制的可能性，使用脉冲电声方法测量带中的空间电荷分布。在使用多层样品的实验中，观察到可能对应于药物的负电荷从具有药物的带移动到不具有药物的带。根据化学分析，认为负电荷可能与药物一致。从这些结果中，有人建议，有一种可能性，即电场将控制药物的运动。

To investigate a possibility of electrical control of a drug in a tape for percutaneous absorption, a space charge distribution using by a pulsed electroacoustic method in a tape were measured. It was observed that negative charge, which might be corresponding to a drug, moved from a tape with a drug to a tape without a drug on an experiment using a multi-layer sample. From the chemical analysis, it was considered that the negative charge might agree with the drug. From these results, it was suggested that there was a possibility that the electrical field would control the movement of a drug.