Eiucidation of the mobilization mechanism of transposab leel ements
Eiucidation of the mobilization mechanism of transposab leel ements
转座子元件动员机制的阐明
批准号：
21770002
负责人：
KAJIKAWA Masaki
金额：
$2.91万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
项目状态：
已结题
起止时间：
2009 至 2010
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Long interspersed elements (LINEs) are transposable elements that mobilize and amplify their own copies within eukaryotic genomes. LINEs mobilize via a mechanism called retrotransposition, in which transcribed LINE RNA is reverse transcribed into DNA that is then integrated into the host chromosome. Although the role of LINE-encoded proteins in retrotransposition has been revealed, the participation of host-encoded proteins has not been well investigated. Here, we present genetic evidence that the host-encoded proteins involved in repair of DNA double-strand breaks participate in LINE retrotransposition.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Host factors are involved in the 5' joining of the LINE integration.
主机因素参与 LINE 集成的 5 连接。
主机因素参与 LINE 集成的 5 连接。
DOI：
--
发表时间：
2010
期刊：
影响因子：
--
作者：
[Kajikawa M.Yamaguchi K., Okada N.]
通讯作者：
Okada N.
DOI：
10.1371/journal.pgen.1000461
发表时间：
2009-04
期刊：
PLoS genetics
影响因子：
4.5
作者：
[Suzuki J, Yamaguchi K, Kajikawa M, Ichiyanagi K, Adachi N, Koyama H, Takeda S, Okada N]
通讯作者：
Okada N
Host factors are involved in the 5' joining of the LINE integration
LINE 集成的 5 连接涉及主机因素
LINE 集成的 5 连接涉及主机因素
DOI：
--
发表时间：
2010
期刊：
影响因子：
--
作者：
[Masaki Kajikawa, Katsumi Yamaguchi, Norihiro Okada]
通讯作者：
Norihiro Okada
The role of host factors in LINE retrotransposition
-
批准号：23770004
-
项目类别：Grant-in-Aid for Young Scientists (B)
-
资助金额：$2.91万
-
财政年份：2011
-
负责人：KAJIKAWA Masaki
-
依托单位：
海外基金
