Three-dimensional structure of lipid-raft localized membrane protein and elucidation of the mechanism forming membrane vesicles

气孔蛋白和漂浮蛋白位于脂筏中，参与膜泡的形成。到目前为止，还没有阐明这些蛋白质的功能。我尝试使用大肠杆菌制备蛋白质，人的气孔蛋白和flotillin，并确定三维结构，以阐明其功能。我成功地得到了这些蛋白质。如果我能得到这些蛋白质的晶体，我就能确定它们的结构。

Stomatin and flotillin, which are involved in forming membrane vesicles, are located in lipid rafts. Until now, it is not elucidated how these proteins function. I tried to prepare proteins, human stomatin and flotillin using Escherichia coli, and to determine three-dimensional structures in order to elucidate their functions. I succeeded to get these proteins. And if I can get crystals of these proteins, I will determine the structures.