Elucidation of a mechanism of dehydration or heat stress signal transduction in plants through post-translational regulation of a transcription factor

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Plants increase tolerance to environmental stresses such as drought or heat in response to these stress stimuli. We analyzed the mechanism for the post-translational regulation of the transcription factor DREB2A in the stress response of Arabidopsis. We compared amino acid sequences among DREB2A orthologs in many plant species and analyzed the effects of site-directed mutagenesis on transcriptional activity of DREB2A. From these analyses, a core region that has a serine/threonine cluster was shown to be important for post-translational activation of the DREB2A protein.