Synthesis of multi-substituted aromatic compounds based on controlling regioselectivities of benzyne reactions

研究了在温和条件下生成的胺与3-硅基苯的区域选择性亲核加成反应和3-苯的Diels-Alder反应。这些新反应可以看作是广泛的多取代芳香族化合物的合成方法，因为芳香族环上的硅和硼取代基可以转化为各种官能团。

The regioselective nucleophilic addition reaction of amines to 3-silylbenzynes and Diels-Alder reaction of 3-borylbenzynes, both of which are generated under mild conditions, have been developed. These new reactions can be regarded as the synthetic methods of broad multi-substituted aromatic compounds because silicon and boron substituents on aromatic ring can be converted to various functional groups.