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Activation mechanism and functional analysis of insect cytokine PP on innate immune response

Activation mechanism and functional analysis of insect cytokine PP on innate immune response
昆虫细胞因子PP对先天免疫反应的激活机制及功能分析
批准号:
21790063
负责人:
HAMAMOTO Hiroshi
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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中文摘要
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英文摘要
Insect cytokine PP (paralytic peptide) induce expression of genes for antimicrobial peptide via p38 MAPK pathway in fat body, and activate the phagocytic activity of hemocytes. Regarding the activation of PP, midgut has important role for recognition of cell wall components of bacteria and secret PP-activating factors. In this research, outline of function and activation mechanism of PP in innate immunity response was revealed.
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会议论文
The insect cytokine paralytic peptide (PP) induces cellular and humoral immune responses in the silkworm Bombyx mori,
昆虫细胞因子麻痹肽 (PP) 诱导家蚕 Bombyx mori 的细胞和体液免疫反应,
DOI: --
发表时间: 2010
期刊: J Biol Chem 285
影响因子: --
作者: [Ishii K, Hamamoto H, Kamimura M, Nakamura Y, Noda H, Imamura K, Mita K, Sekimizu K]
通讯作者: Sekimizu K
DOI: 10.5582/ddt.v5.1.18
发表时间: 2011-01-01
期刊: DRUG DISCOVERIES AND THERAPEUTICS
影响因子: 3.1
作者: [Dhital, Saphala, Hamamoto, Hiroshi, Sekimizu, Kazuhisa]
通讯作者: Sekimizu, Kazuhisa
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [浜本洋, 堀江亮, 関水和久]
通讯作者: 関水和久
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [堀江亮, 浜本洋, 関水和久]
通讯作者: 関水和久
21
    Development of lead commands for new anti-infective agents
    • 批准号:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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    • 财政年份:
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    • 负责人:
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