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Development of a biomarker for assessing exposure to quinone compounds associated with producing reactive oxygen species

Development of a biomarker for assessing exposure to quinone compounds associated with producing reactive oxygen species
开发用于评估与产生活性氧相关的醌化合物暴露的生物标记物
批准号:
21790126
负责人:
TORIBA Akira
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

项目摘要

项目成果

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中文摘要
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英文摘要
9,10-Phenanthrenequinone (PQ) has been suspected to be a causative factor in cardiovascular and allergic diseases which have been reported to be oxidative stress-related disorders. To develop a biological marker (biomarker) for assessing human exposure to PQ, an analytical method has been developed to determine urinary metabolites of PQ in human urine. For the first time, PQ metabolites in human urine were identified using the developed method.
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会议论文
Atmospheric Formation of Hydroxynitropyrenes from a Pilotochemical Reaction of Particle-Associated 1-Nitropyrene
颗粒缔合 1-硝基芘的中试化学反应在大气中形成羟基硝基芘
DOI: --
发表时间: 2011
期刊: Environ.Sci.Technol.
影响因子: --
作者: [中瀬生彦, 二木史朗, Takayuki Kameda]
通讯作者: Takayuki Kameda
DOI: 10.1016/j.mrgentox.2009.10.010
发表时间: 2010
期刊: Mutation research
影响因子: --
作者: [Xiaoyang Yang;Kazuhiko Igarashi;N. Tang;Jin-Ming Lin;Wei Wang;T. Kameda;A. Toriba;K. Hayakawa]
通讯作者: Xiaoyang Yang;Kazuhiko Igarashi;N. Tang;Jin-Ming Lin;Wei Wang;T. Kameda;A. Toriba;K. Hayakawa
DOI: 10.1021/es802392u
发表时间: 2010-01-01
期刊: Environmental science & technology
影响因子: 11.4
作者: [Miller-Schulze JP, Paulsen M, Toriba A, Tang N, Hayakawa K, Tamura K, Dong L, Zhang X, Simpson CD]
通讯作者: Simpson CD
Urinary 1-nitropyrene metabolites as a biomarker for exposure to nitropolycyclic aromatic hydrocarbons
尿液 1-硝基芘代谢物作为硝基多环芳烃暴露的生物标志物
DOI: --
发表时间: 2022
期刊:
影响因子: --
作者: [Hirai Anri, Sugio Shouta, Nimako Collins, Nakayama Shouta M. M., Kato Keisuke, Takahashi Keisuke, Arizono Koji, Hirano Tetsushi, Hoshi Nobuhiko, Fujioka Kazutoshi, Taira Kumiko, Ishizuka Mayumi, Wake Hiroaki, Ikenaka Yoshinori, Haruhiko Nakata,Hiroto Yamada,Koshiro Eto,Shinsuke Tanabe,Tatsuya Kunisue, 鳥羽 陽]
通讯作者: 鳥羽 陽
22
    Development of a method for assessing human exposure to cross-boundary air pollutions by polycyclic aromatic sulfur heterocyclic compounds as chemical markers
    • 批准号:
      24590160
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.49万
    • 财政年份:
      2012
    • 负责人:
      TORIBA Akira
    • 依托单位:
    International comparative research on exposure and biological effects of air pollution for local residents in Asia
    • 批准号:
      23406004
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $5.24万
    • 财政年份:
      2011
    • 负责人:
      TORIBA Akira
    • 依托单位:
    The research on the evaluation method for the endocrine-disrupting effect of benzo[a]pyrene and its metabolites
    • 批准号:
      13558066
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $6.27万
    • 财政年份:
      2001
    • 负责人:
      TORIBA Akira
    • 依托单位:
    海外基金