CommonMechanismforCancerProgressionandStratificationofEpithelia
CommonMechanismforCancerProgressionandStratificationofEpithelia
批准号:
21790267
负责人:
MATSUI Takeshi
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2012
中文摘要
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英文摘要
Skin-specific secreted peptide, dermokine was expressed in colorectal and pancreatic cancer at the early-stageof carcinogenesis. Serum dermokine was potential biomarker in these cancers. In addition, activity of skin-specific protease, SASPase plays a key role in stratum corneum hydration through profilaggrin processing. SASPase was also expressed at the early-stage of carcinogenesis. These results suggested the potential link between cancer progression and stratification of epithelia.
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Mammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization and Evolution. RSC-iCeMS Joint IaMammalian Skin-specific Retroviral-like Aspartic Protease, SASPase is a Key Modulator of Skin Moisturization and
哺乳动物皮肤特异性逆转录病毒样天冬氨酸蛋白酶,SASPase 是皮肤保湿和进化的关键调节剂。
DOI:
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发表时间:
2012
期刊:
影响因子:
--
作者:
[藤田佳子, 垣野明美, 乙井一典, 山口三郎, 佐藤優子, 小倉紗世子, 岩元真, 沢村達也, Hideo Shindou., Matsui T]
通讯作者:
Matsui T
Evolutionally integrated retroviral-like aspartic protease, SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing
进化整合的逆转录病毒样天冬氨酸蛋白酶,SASPase 通过聚丝蛋白原到聚丝蛋白加工调节角质层水合作用
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[松井 毅, 松井 毅, 松井 毅, Matsui T]
通讯作者:
Matsui T
Analysis and clinical application of dermokines, stratified epithelia-specific secreted proteins
皮肤因子、复层上皮特异性分泌蛋白的分析及临床应用
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Tanahashi S, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M, Matsui T, Matsui T, Matsui T]
通讯作者:
Matsui T
表皮の顆粒層特異的に発現するプロテアーゼSASPaseによる、角質層水分量の制御機構
SASPase(一种在表皮颗粒层特异性表达的蛋白酶)对角质层含水量的控制机制
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[松井毅, 宮本憲, 久保亮治, 川崎洋, 海老原全, 畑和也, 市野瀬志津子, 井本逸勢, 稲澤譲治, 工藤純, 天谷雅行, Matsui T]
通讯作者:
Matsui T
Treatment of Dry Skin Syndrome -The Art and Science of Moisturizers-
干燥皮肤综合症的治疗 - 保湿霜的艺术与科学 -
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[Matsui T, Miyamoto K, Kubo A, Kawasaki H, Ebihara T, Hata K, Tanahashi S, Ichinose S, Imoto I, Inazawa J, Kudoh J, Amagai M, Matsui T, Matsui T, Matsui T, 松井毅, Matsui T, Matsui T, T Matsui]
通讯作者:
T Matsui
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