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Control of tumor formation after transplantation in regenerative therapy with genetic engineering methods

Control of tumor formation after transplantation in regenerative therapy with genetic engineering methods
基因工程方法再生治疗中移植后肿瘤形成的控制
批准号:
21790528
负责人:
TAHARA Tsuyoshi
金额:
$2.75万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010

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英文摘要
Gene therapy and cell transplantation therapy is expected to be a breakthrough for treating neurodegenerative disorders, such as Parkinson's and Alzheimer's disease. In this study, I could isolate the tumor- or non-differentiated cell-specific promoter region from Oct3/4 gene promoter and make the GFP expression vector, which works only in non-differentiated cell, such as mouse embryonic EB5 cell but not mouse fibroblast Balb/3T3b cells.
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Transcriptional regulation of the neuroglobin gene expression in neural cells
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