Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese

日本人血浆不对称二甲基精氨酸与 7 年冠状动脉钙化发生率的关系

• 批准号: 21790578
• 负责人: NAGASAWA Shin-ya
• 金额: $ 2.83万
• 依托单位: Shiga University of Medical Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21790578/
• 关键词: 成人保健; 心腎連関

Findings on the relationship of plasma asymmetrical dimethylarginine (ADMA) to atherosclerosis have been scarce. And the finding about relationship to the future incidence of coronary artery calcification (CAC) has been lack.We attempted to evaluate the association in a 7-year follow-up of population-based samples in Japan.Higher level of ADMA was independently associated with the future incidence of CAC in Japanese men. ADMA may be a new important predictor for progression of atherosclerosis.

关于血浆不对称二甲基精氨酸（ADMA）与动脉粥样硬化关系的研究很少。我们试图通过对日本人群样本的7年随访来评估其与冠状动脉钙化（CAC）的关系，发现日本男性中较高水平的ADMA与CAC的未来发病率独立相关。ADMA可能是动脉粥样硬化进展的一个新的重要预测因素。

项目成果

Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese : the ERA-JUMP Study

日本人血浆不对称二甲基精氨酸与 7 年冠状动脉钙化发生率的关系：ERA-JUMP 研究

• 发表时间: 2011
• 作者: 山本泰資;樋口倫代;川口レオ;大橋亜由美;青山温子;長澤晋哉
• 通讯作者: 長澤晋哉

Relationship of plasma asymmetrical dimethylarginine to 7-year incidence of coronary artery calcification in Japanese : the ERA-JUMP Study.

日本血浆不对称二甲基精氨酸与 7 年冠状动脉钙化发生率的关系：ERA-JUMP 研究。

• 发表时间: 2011
• 作者: 青山温子;川口レオ;樋口倫代;江啓発;Shin-ya Nagasawa.
• 通讯作者: Shin-ya Nagasawa.