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The epidemiological study that a heart rate at rest lets metabolic syndrome progress

静息心率导致代谢综合征进展的流行病学研究

基本信息

批准号：
21790589
负责人：
SATOH Akira
金额：
$ 2.75万
依托单位：
Kurume University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2009
资助国家：
日本
起止时间：
2009 至 2010
项目状态：
已结题

项目摘要

I considered whether a heart rate at rest let metabolic syndrome progress by general inhabitants examination. I carried out inhabitants examination and performed the data collection of testee 1,943 people in total, analysis. The rest average heart rate of the testee divided it into four groups more than less than 60, 61-69, 70-79, 80 a minute at 64.7+-10 a minute and analyzed it about the connection with each item. Blood sugar, an insulin level, HOMA index, an LDL cholesterol level, an aldosterone level, an active form renin level significantly rose to the heart rate that they revised by age and the nature at rest as a group with many heart rates in for the shrinkage period and diastolic blood pressure, the uric acid level, fasting. The heart rate at rest participated with blood pressure to constitute metabolic syndrome, insulin resistance and lipid metabolism clearly and recognized an aldosterone level in conjunction with the sympathetic nerve activity, the connection that were meaningful with the active form renin level, and the possibility that sympathetic nerve activity was related to progress of the metabolic syndrome was suggested. However, the number of the aging was short, and there were few numbers of people that metabolic syndrome developed in, and, in the observation period from 2009 through 2011, the meaningful connection was not provided for a heart rate and onset progress of the metabolic syndrome. I am going to follow it in future.

通过普通居民检查，我考虑了安静时的心率是否会让代谢综合征进展。我进行了居民调查，共收集了1,943人的数据，进行了分析。受试者的其余平均心率以每分钟64.7+-10的速度分为每分钟小于60、61-69、70-79、80四组，并分析其与每一项目的关系。血糖、胰岛素水平、HOMA指数、低密度脂蛋白胆固醇水平、醛固酮水平、活性肾素水平显著上升到他们根据年龄和休息性质修正的心率，作为一个组，在收缩时期和舒张压、尿酸水平、空腹时有许多心率。静息心率与血压共同参与构成代谢综合征、胰岛素抵抗和脂代谢，明确地认识到与交感神经活动有关的醛固酮水平，与活动形式肾素水平有意义的联系，提示交感神经活动与代谢综合征进展有关的可能性。然而，老龄化的人数很少，代谢综合征的发病人数也很少，而且在2009年至2011年的观察期内，心率与代谢综合征的发病进程没有提供有意义的联系。我将在未来遵循它。