Doesaggressiveintravenousnutritionimprovedevelopmentofpreterminfants?-Eliminatingextrauterinegrowthrestriction.

在一项研究中，调查了早产儿9岁时常规脑MRI与认知结果之间的关系，观察到白色损伤与认知、语言和运动障碍之间存在显著相关性。在另一项对82名足月早产儿进行的弥散张量成像研究中，白色物质的各向异性分数与婴儿的受孕后年龄呈线性相关。参与者还评估了出生后18个月和36个月的神经发育结果;目前正在分析新生儿期背景临床变量（包括营养和定量MRI标记物）与神经发育结果之间的详细关系。

In a study which investigated the relationship between conventional brain MRI at term and the cognitive outcome at 9 years old in very preterm-born infants, significant correlations were observed between the white matter injury and cognitive, language and motor impairment. In another study using diffusion tensor imaging at term in 82 preterm infants, fractional anisotropy of the white matter was linearly correlated with the postconception age of the infant. Participants were also assessed for the neurodevelopmental outcome at 18 and 36 months of post-natal corrected age ; detailed relationships between background clinical variables during the neonatal period including nutrition and quantitative MRI markers and neurodevelopmental outcomes are currently under analysis.