Histological analysis of paraspinal muscle degeneration and regeneration.

术后椎旁肌退变伴术中损伤被认为是影响手术临床效果的因素之一。本研究的目的是证明腰椎棘突劈开椎板切除术的微创性，这是一种保留肌肉的技术。我们用大鼠模型评估腰椎后路减压术后棘旁肌的退变。通过组织学和生物学评估，我们证明了劈开椎板切除术可以最大限度地减少术中对肌肉的损伤和术后肌肉的萎缩。

Postoperative degeneration of paraspinal muscle associated with intraoperative damages has been regarded as a factor which deteriorate clinical result of the surgery. Purpose of this study was to demonstrate the less invasiveness of lumbar spinous process splitting laminectomy, the muscle preserving technique. We have evaluated the degeneration of the paraspinal muscle after lumbar posterior decompression surgery using rat model. As a result of histological and biological evaluation, we demonstrated that the split laminectomy could minimize the intraoperative damages to the muscles and postoperative atrophy of the muscles.