The relationships between the compensatory hypertrophy in the donor's residual kidney and the renal function of the allograft or hemi-nephrectomized donor

供体残肾代偿性肥厚（CH）可能导致移植肾GFR升高。我们评估了组织生长因子（如IGF-1或GH）基因多态性与供体残肾CH之间的关系。此外，我们还调查了供者残肾中的CH是否影响半肾切除供者的肾功能和预后。在本研究中，我们无法评估组织生长因子基因多态性与供肾代偿性肥大发生率等临床数据之间的关系。在免疫组化研究中，我们无法评估它们，因为几乎所有的0小时活检标本都呈阴性染色。几乎所有的捐赠者都保持了良好的肾功能。供者肾脏代偿性肥大的发生率与供者肾功能受损或死亡之间没有关系。

Compensatory hypertrophy (CH) in the donor's residual kidney may induce a higher GFR in the transplanted kidney. We evaluated the relationship between the gene polymorphisms of tissue growth factor such as IGF-1 or GH and the CH in the donor's residual kidney. In addition, we surveyed whether the CH in the donor's residual kidney affect the renal function of hemi-nephrectomized donor and the prognosis of donor.In this study, we coudn't evaluate the relationship between the gene polymorphisms of tissue growth factor and clinical data including the incidence of compensatory hypertrophy of the donor kidney. In the immunohistochemical study, we couldn't evaluate them because almost all of 0 hour biopsy specimens showed negative staining. Almost all donors kept the renal function well. There was no relationship between the incidence of compensatory hypertrophy of the donor kidney and the donors who impaired the renal function or died.