Unfolded protein response in age related macular degeneration and retinal degeneration.
Unfolded protein response in age related macular degeneration and retinal degeneration.
批准号:
21791677
负责人:
KACHI Shu
金额:
$2.66万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
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英文摘要
It is reported that amyloid beta stimulates the vascular endothelial growth factor (VEGF) expression from the retinal pigment epithelium (RPE) cells. We found that amyloid beta also increases the expression of the unfolded protein response (UPR) markers. These increases of VEGF and UPR were down-regulated by addition of 4-phenylbutyric acid (PBA), UPR inhibitor, to the medium.
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A case of acute retinal necrosis after corticosteroid pulse therapy for unilateral Vogt-Koyanagi-Harada disease.
单侧 Vogt-小柳-原田病皮质类固醇冲击治疗后发生急性视网膜坏死一例。
DOI:
--
发表时间:
2010
期刊:
Retinal Cases & Brief Reports. 4(1)
影响因子:
--
作者:
[Yokoi R, Asami T, Kachi S, Ito Y, Nakamura M, Terasaki H.]
通讯作者:
Terasaki H.
Intravitreal injection of bevacizumab for macular edema secondary to BRVO : Results after 12-months and multiple regression analysis.
玻璃体内注射贝伐单抗治疗 BRVO 继发性黄斑水肿:12 个月和多元回归分析后的结果。
DOI:
--
发表时间:
2009
期刊:
Retina 29
影响因子:
--
作者:
[Kondo M, Kondo N, Ito Y, Kachi S, Kikuchi M, Yasuma TR, Ota I, Kensaku M, Terasaki H., Yamakoshi T, Nonobe NI, Kondo M]
通讯作者:
Kondo M
加齢黄斑変性に対するPDTと抗VEGF療法
PDT 和抗 VEGF 疗法治疗年龄相关性黄斑变性
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[伊島亮, 安田俊介, 加地秀, 近藤峰生, 寺崎浩子, 牛田宏昭, 加地秀, 伊島亮, 加地秀]
通讯作者:
加地秀
The distribution and characteristics of bone marrow-derived cells in the retina during physiological and pathological angiogenesis.
生理和病理性血管生成过程中骨髓来源细胞在视网膜中的分布和特征。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Kataoka K, Nishiguchi KM, Kachi S, Terasaki H, Kataoka K]
通讯作者:
Kataoka K
網膜中心静脈閉塞症における眼内血管内皮増殖因子濃度と網膜電図
视网膜中央静脉阻塞眼内血管内皮生长因子浓度和视网膜电图
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[安田俊介, 加地秀, 近藤峰生, 牛田宏昭, 植谷留佳, 照井隆行, 朴昌華, 寺崎浩子]
通讯作者:
寺崎浩子
共 43 条
The influence of unfolded protein response on age related macular degeneration.
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批准号:23592563
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2011
-
负责人:KACHI Shu
-
依托单位:
Use of Magnetite Cationic Liposome for Gene Transfection to Ocular Cells and in vivo Promoter Analysis
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批准号:19791262
-
项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.05万
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财政年份:2007
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负责人:KACHI Shu
-
依托单位:
海外基金