Molecular biological studies on the effect of Candida albicans on invasion of host cells by pe riodontopathic bacteria.
Molecular biological studies on the effect of Candida albicans on invasion of host cells by pe riodontopathic bacteria.
批准号:
21791795
负责人:
TAMAI Riyoko
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
热杀死白色念珠菌(HKCA)和白色念珠菌水溶性甘露蛋白-β-葡聚糖复合物(CAWS)没有上调牙龈卟啉单胞菌对人牙龈上皮细胞和牙龈成纤维细胞的粘附以及牙龈卟啉单胞菌侵袭所需的β1整合素和ICAM-1的表达。而HKCA和CAWS可促进牙龈假单胞菌对人牙龈上皮细胞和成纤维细胞的侵袭。
英文摘要
Heat-killed Candida albicans (HKCA) and water-soluble mannoprotein-β-glucan complex from C. albicans (CAWS) did not up-regulate adhesion of Porphyromonas gingivalis to human gingival epithelial cells and gingival fibroblasts and expression of β1 integrin and ICAM-1, which are required for P.gingivalis invasion, on the cells. However, HKCA and CAWS promoted invasion of human gingival epithelial cells and gingival fibroblasts by P.gingivalis.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
菌体成分に対する宿主細胞の反応における真菌の増悪効果に関する研究
真菌加重宿主细胞对细菌成分反应的研究
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[玉井利代子, 清浦有祐]
通讯作者:
清浦有祐
The effect of heat-killed Candida albicans on the response of macrophages to bacterial components
热灭活白色念珠菌对巨噬细胞对细菌成分反应的影响
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[玉井利代子, 清浦有祐]
通讯作者:
清浦有祐
Molecular biological studies on the effects of fungi on invasion of host cells by periodontalpathogenic bacteria
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批准号:23592709
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.41万
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财政年份:2011
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负责人:TAMAI Riyoko
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依托单位:
海外基金