The relationship of intraepithelial blood vessels and NBI system in oral borderline malignancies.

通过免疫组织化学检查口腔交界性恶性肿瘤（包括上皮发育不良和原位癌（CIS））上皮区（IEBV）内的毛细血管中的 CD31 和 IV 型胶原。 CIS 中 IEBV 的数量显着增加。研究表明，窄带成像（NBI）是为了可视化异常微血管模式而建立的，是鉴别诊断口腔交界性恶性肿瘤和确定足够安全裕度的有效工具。

Blood capillary vessels within the epithelial zone(IEBVs) of oral borderline malignancies including epithelial dysplasia and carcinoma in-situ(CIS) were examined by immunohistochemistry for CD31 and type IV collagen. IEBVs increased in number significantly in CIS. It was revealed that narrow band imaging(NBI), that is established to visualize abnormal microvascular patterns was a effective tool for differential diagnosis of oral borderline malignancies and decision of a adequate safety margin.