The relationship of intraepithelial blood vessels and NBI system in oral borderline malignancies.

应用免疫组织化学方法检测口腔交界性恶性肿瘤(包括上皮异型增生和原位癌)上皮区毛细血管CD31和IV型胶原的表达。在独联体中IEBV的数量显著增加。结果表明，窄带成像(NBI)是一种有效的鉴别诊断方法，可显示口腔交界性肿瘤的异常微血管模式，并可确定适当的安全范围。

Blood capillary vessels within the epithelial zone(IEBVs) of oral borderline malignancies including epithelial dysplasia and carcinoma in-situ(CIS) were examined by immunohistochemistry for CD31 and type IV collagen. IEBVs increased in number significantly in CIS. It was revealed that narrow band imaging(NBI), that is established to visualize abnormal microvascular patterns was a effective tool for differential diagnosis of oral borderline malignancies and decision of a adequate safety margin.