Detection of new ion channel in the nerve terminals of the periodontal ligament
Detection of new ion channel in the nerve terminals of the periodontal ligament
批准号:
21792064
负责人:
HARADA Fumiko
金额:
$2.83万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2009
资助国家:
日本
项目状态:
已结题
起止时间:
2009 至 2010
中文摘要
据报道,酸感离子通道3 (ASIC3)参与酸感、机械感觉和伤害感受。本研究采用免疫组化方法检测ASIC3在小鼠切牙舌周韧带中的表达。此外,ASIC3在三叉神经节(支配牙周韧带)中的表达在蛋白和mRNA水平上进行了研究。这些发现表明ASIC3在牙周Ruffini末梢中作为机械感觉分子起作用。
英文摘要
The acid-sensing ion channel 3 (ASIC3) has been reported to participate in acid sensing, mechanosensation, and nociception. The present study examined the expression of ASIC3 in the lingual periodontal ligament of mouse incisors by immunohistochemistry. Furthermore, the expression of ASIC3 in the trigeminal ganglion-which innervates the periodontal ligament-was investigated at protein and mRNA levels. These findings suggest that ASIC3 functions as a molecule for mechanosensation in the periodontal Ruffini endings.
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DOI:
10.1016/j.neulet.2010.11.023
发表时间:
2011-01-20
期刊:
NEUROSCIENCE LETTERS
影响因子:
2.5
作者:
[Rahman, Farhana, Harada, Fumiko, Maeda, Takeyasu]
通讯作者:
Maeda, Takeyasu
GDNF expression in terminal schwann cells associated with the periodontal Ruffini endings of the rat incisors during nerve regeneration.
神经再生过程中与大鼠门牙牙周鲁菲尼末梢相关的终末雪旺细胞中 GDNF 的表达。
DOI:
--
发表时间:
2009
期刊:
Anatomical Record 292
影响因子:
--
作者:
[Ohishi M, Harada F, et al.]
通讯作者:
et al.
Acid-Sensing Ion Channel 3 Expression in the Periodontal Ruffini Endings.
牙周 Ruffini 末梢中酸敏感离子通道 3 的表达。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Rahman F, Harada F, Kawano Y, Ohishi M, Nozawa-Inoue K, Saito I, Maeda T.]
通讯作者:
Maeda T.
Acid-Sensing Ion Channel 3 Expression in the Periodontal Ruffi ni Endings.
牙周 Ruffini 末梢中酸敏感离子通道 3 的表达。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Rahman F, Harada F, Kawano Y, Ohishi M, Nozawa-Inoue K, Saito I, Maeda T.]
通讯作者:
Maeda T.
Multiple neurotrophins involve regeneration of the periodontal Ruffini endings after transection of rat inferior alveolar nerve.
多种神经营养因子涉及大鼠下牙槽神经横断后牙周鲁菲尼末梢的再生。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Ohishi M, Harada F, Maeda T.]
通讯作者:
Maeda T.
共 6 条
Development of Reduction Method of Management Cost in Mud-slide Detection Sensor Network
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批准号:22700111
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.5万
-
财政年份:2010
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负责人:HARADA Fumiko
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依托单位:
Neural-glial interaction during the tooth movement mediated by the water-selective channel
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批准号:19791571
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$2.38万
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财政年份:2007
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负责人:HARADA Fumiko
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依托单位:
QoS-aware low-power consumption resource scheduling for sensor network systems
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批准号:19800053
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项目类别:Grant-in-Aid for Young Scientists (Start-up)
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资助金额:$1.99万
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财政年份:2007
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负责人:HARADA Fumiko
-
依托单位:
海外基金