Proteomic analysis of anhydrobiotic and extremotolerant animal

我们从无水缓步动物Ramazzottius varieornatus中鉴定出几个新的抗聚集蛋白，并发现这些蛋白在活性状态下也大量表达。虽然这些蛋白是在较不耐受性的taridiades中发现的，但它们的变性温度和干燥耐受性之间存在一定的相关性。我们所鉴定的蛋白质为阐明缓步动物无水能力和极端耐受性的分子机制提供了良好的基础。

We identified several novel anti-aggregation proteins from an anhydrobiotic tardigrade, Ramazzottius varieornatus and revealed that these proteins were expressed abundantly even in active state. Although these proteins were found in less-tolerant taridirades, there are some correlation between their denaturing temperature and desiccation-tolerance. Our identified proteins are good basis to elucidate the molecular mechanism of anhydrobiotic ability and extremotolerance of tardigrades.