Development of a new micelle nanobubble and ultrasoundcombination cancer chemotherapy

前列腺素E_1(PGE_1)Liple是前列腺素E_1的药物。这种药物是一种以胶束形式存在的药物释放系统。在目前的实验中，设计了一种高速混合装置，以将气体捕获到其结构中。分析测量结果表明，治疗前后的大小至少在3-10μm的范围内有显著差异，这一新的空气滞留胶束可以作为超声成像的造影剂和各种药物的释放剂，包括前列腺素E_1。

Prostaglandin E1(PGE1)Liple is the medication of prostaglandin E1. This drug is a drug delivery system which is in the form of micelles. In the current experiments, a high speed mixing device was devised to entrap gas within its structure. Analysis measurement resulted in significant difference in size before and after treatment at least in the range of 3-10 μm. It was strongly suggested that this new air trapped micelles could act as a contrast agent for ultrasound imaging and for delivery of various drugs, including prostaglandin E1.