Environmental whole body adaptation during human locomotion -specific linkage among lung, circulation, and muscle functions-

人体运动过程中的环境全身适应——肺、循环和肌肉功能之间的特定联系——

• 批准号: 22370091
• 负责人: FUKUOKA Yoshiyuki
• 金额: $ 11.56万
• 依托单位: Doshisha University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22370091/
• 关键词: 環境適応; 全身的協関; 歩行; 老化; 生理的多型性

To investigate the integrative physiological linkage among ventilatory, circulatory, and metabolic functions during the locomotion with varying sinusoidal speed at the periods for 1, 2, 5, and 10 min, fours experimental verifications would be accomplished. The abrupt and additional ventilatory response could elicit during sinusoidal walking rather than during sinusoidal cycling. The underlying mechanism, by which the supura-spinal locomotion center would contribute on in partly during human locomotion, was testified compared to human cycling. Secondly, aging and hypoxic exposure directly reflected on the central ciriculatory response, i.e., heart rate, rather than gas exchange kinetics, the delayed HR kinetics during sinusoidal walking was attributed to the sympathetic activation in the elderly individuals. Thirdly, kinetics of capillary blood flow in exercising muscle using the NIRS technique became significantly faster than HR and gas exchange kinetics and could be compensated on the delayed ventilatory and gas exchange kinetics during human locomotion.

为了研究在1、2、5和10 min的时间段内以不同正弦速度运动期间的消化、循环和代谢功能之间的综合生理联系，将完成四个实验验证。正弦曲线行走比正弦曲线骑车更能引起突然的和额外的痉挛反应。通过与人类自行车运动的比较，证实了脊髓上运动中枢在人类运动中的部分作用机制。其次，衰老和低氧暴露直接反映在中枢循环反应上，即，心率，而不是气体交换动力学，在正弦步行期间延迟的HR动力学归因于老年个体中的交感神经激活。第三，使用NIRS技术的运动肌肉中的毛细血管血流动力学变得明显快于HR和气体交换动力学，并且可以补偿人体运动期间延迟的舒张和气体交换动力学。

项目成果

Phosphocreatine resynthesis during recovery in different muscles of the exercising leg by 31P-nuclear magnetic resonance spectroscopy.

通过 31P 核磁共振波谱观察运动腿部不同肌肉恢复过程中磷酸肌酸的再合成。

• DOI: 10.1111/sms.12081
• 发表时间: 2013
• 期刊: Scand J Med Sci Sports
• 作者: Yoshida Y;Abe D;and Fukuoka Y.
• 通讯作者: and Fukuoka Y.

注排水による不感温浸水負荷が回復期急性心筋梗塞患者の循環応答に与える影響

注水不敏感水浸负荷对急性心肌梗死患者恢复期循环反应的影响

• 发表时间: 2012
• 期刊: 日本心臓リハビリテーション学会誌
• 作者: 伊藤雅浩;小島 淳;坂本知浩;福岡義之;小川久雄
• 通讯作者: 小川久雄

酸素摂取動態のモデル化、「身体運動と呼吸・循環機能」

吸氧动力学建模，“体育锻炼和呼吸/循环功能”

• 发表时间: 2012
• 作者: Katsumura T;Oda S;Mitani H; Kawamura S;Oota z H.;福場良之
• 通讯作者: 福場良之

Post-exercise hypotension : The effect of water drinking during exercise

运动后低血压：运动期间喝水的影响

• 发表时间: 2010
• 作者: Fukuba Y;Kajimoto C;Yamada M;Koga S;Endo MY
• 通讯作者: Endo MY

Blood pressure response during recovery after moderate leg cycling exercise in humans

人类适度腿部骑自行车运动后恢复期间的血压反应

• 发表时间: 2010
• 作者: 熊倉博雄;岡健司;後藤遼佑;Fukuba Y
• 通讯作者: Fukuba Y