Elucidation of mechanisms involved in formation of yolk granules and lipid droplets in fish

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The objective of this study is to elucidate mechanisms involved in the formation of "yolk granules/globules (YGs)" and "lipid droplets (LDs)", which are major components of fish egg yolk. Results revealed profiles of YG precursors (vitellogenins) and LD precursors (various lipoproteins), as well as their corresponding ovarian receptors (lipoprotein receptors); these findings resulted in constructing and proposing a novel and complicated model for fish yolk formation, which will also help to progressively regulate oocyte growth and improve egg quality in aquaculture fishes in future.