Elucidation of the evasion mechanism of cytokine storm in disease resistant native livestock

在非洲、亚洲和南美国家，本土牲畜相对来说是一种抵抗疾病的动物，但它们可能会被传染病病原体感染。因此，有必要对疾病发展过程中的免疫学事件进行研究。我们的研究表明，在感染伊氏锥虫(苏拉病的病原体)和微小毛滴虫(东方成本热的病原体)的本地动物中，存在作为包括细胞因子风暴在内的炎症反应的潜在调节的调节性DC的子集的增加。

In African, Asian and South American countries, native livestock is relatively a disease-resistant animal, but they can be infected with infectious agents. Therefore, there is a need to investigate the immunological events during disease development. Our study has shown that, in T. evansi (causative agent for Sura disease) and T. parva (causative agent for East Cost fever)-infected native animals, there is an augmentation of a subset of regulatory DCs that act as potential regulators of the inflammatory responses including cytokine storm.