Clinical application of preload stress echocardiography with leg-positive pressure in patients with chronic heart failure

应用预负荷负荷超声心动图对轻度心力衰竭患者进行下肢正压（LPP）检查。根据传递血流速度模式将患者分为3组：休息时限制性或假性（PN），休息和LPP期间松弛受损（IR）（稳定IR），休息时IR和LPP期间PN（不稳定IR）。不稳定IR组的全因心脏事件发生率高于稳定IR组，PN组的全因心脏事件发生率相似。不稳定IR的无事件生存率低于稳定IR。预负荷负荷超声心动图为轻度心力衰竭患者提供了常规超声心动图参数之外的额外预后信息。

Preload stress echocardiography was applied with leg-positive pressure (LPP) in patients with mild heart failure. Patients were classified into 3 groups based on transmitral flow velocity pattern: restrictive or pseudontrmal (PN) at rest, impaired relaxation (IR) at rest and during LPP (stable IR), and IR at rest and PN during LPP (unstable IR). All-cause cardiac event rate was higher in unstable IR than in stable IR, and was similar in PN group. Event-free survival was lower in unstable IR than stable IR. Preload stress echocardiography provides additional prognostic information in mild heart failure patients beyond conventional echocardiographic parameters.