Detoxication of fluorine-bearing pharmaceutical drugs by advanced oxidation processes

含氟药物作为内分泌干扰物，对生态水体环境造成严重污染。在添加臭氧和/或过氧化氢的高级氧化过程中，导致了顽固化学物质的解毒。为了切断强C-F键，采用氧化镓催化光辅助脱氟生成氟离子。负载pt的Ga2O3催化剂提高了脱氟收率。研究了除氟的最佳工艺条件。因此，不可降解物质易矿化，其降解中间体经Ames试验无致突变性。

Fluorine-bearing pharmaceuticals are acted as an endocrine disruptor to cause serious contamination in ecological aquatic environment. The advanced oxidation processes in the addition of ozone and/or hydrogen peroxide led the detoxication for recalcitrant chemicals. In order to sever the strong C-F bond, the photoassisted defluorination by gallium oxide catalysis was carried out to generate fluorine ions. The Pt-loading Ga2O3 catalyst enhanced the defluorination yield. The opimal conditions of defluorination were investigated. Therefore, non-degradable substances were easily mineralized and their degraded intermediates had no mutagenicity by the Ames test.