Elucidation of protein modification system with related ubiquitin protein, RUB/Nedd8, in Arabidopsis

阐明拟南芥中相关泛素蛋白 RUB/Nedd8 的蛋白修饰系统

• 批准号: 22570056
• 负责人: OONO Yutaka
• 金额: $ 2.58万
• 依托单位: Japan Atomic Energy Agency
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22570056/
• 关键词: 植物分子機能; ユビキチン様タンパク質; オーキシン; シロイヌナズナ; COP9シグナロゾーム; Nedd8; RUB; ユビキチンE3リガーゼ

Protein modification system by a small protein, RUB/Nedd8, was elucidated with taking into account functional relationship of a novel auxin-signaling factor, SMAP1. Genetic analyses and inhibitor examination revealed that SMAP1 is involved in plant growth and development via its interaction with components associated with RUB/Nedd8 modification.

考虑到一种新的生长素信号因子SMAP1的功能关系，阐明了一种小蛋白RUB/Nedd8的蛋白质修饰系统。遗传分析和抑制物检测表明，SMAP1通过与RUB/Nedd8修饰相关的成分相互作用而参与植物的生长发育。