Study on NADPH oxidase function in development
Study on NADPH oxidase function in development
批准号:
22570140
负责人:
KAMEI Kaeko
金额:
$3.0万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2012
中文摘要
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英文摘要
NADPH (nicotinamide adenine dinucleotide phosphate) oxidase is an enzyme that produces reactive oxygen species. The function of NADPH oxidase in the development, especially in the wing formation, was analyzed using Drosophila. We reveled that NADPH oxidase is essential for normal wing development through the melanin formation and cross-linking of tyrosine for wing sclerotization and the suppression of apoptosis. By genetic screening, the genetic region on 3 rd chromosome that could interact with dDuox (catalytic domain of NADPH oxidase) was found.
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DOI:
10.1074/jbc.m111.263178
发表时间:
2011-09-23
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Nguyen Thi Tu Anh, Nishitani, Maiko, Kamei, Kaeko]
通讯作者:
Kamei, Kaeko
DOI:
10.1007/s11418-009-0357-1
发表时间:
2010-01-01
期刊:
JOURNAL OF NATURAL MEDICINES
影响因子:
3.3
作者:
[Kojima, Hiroaki, Akaki, Junji, Tamesada, Makoto]
通讯作者:
Tamesada, Makoto
DOI:
10.1007/s11010-011-0743-3
发表时间:
2011-02
期刊:
Molecular and Cellular Biochemistry
影响因子:
4.3
作者:
[N. Anh;Maiko Nishitani;S. Harada;M. Yamaguchi;K. Kamei]
通讯作者:
N. Anh;Maiko Nishitani;S. Harada;M. Yamaguchi;K. Kamei
Role of Duox oxidase in wing development of Drosophila melanogaster
Duox氧化酶在果蝇翅膀发育中的作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Nguyen Ti Tu Anh, 西谷真依子, 山口政光, 亀井加恵子]
通讯作者:
亀井加恵子
Neutralization of Toxic Heme by Porphyromonas gingivalis Hemoglobin Receptor.
牙龈卟啉单胞菌血红蛋白受体中和有毒血红素。
DOI:
--
发表时间:
2010
期刊:
J Biochem.
影响因子:
--
作者:
[N.T.Nhien, N.T.Huy, M.Naito, T.Oida, D.T.Uyen, M.Huang, M.Kikuchi, S.Harada, K.Nakayama, K.Hirayama, K.Kamei.]
通讯作者:
K.Kamei.
Role of macrophage mannose receptor in malaria
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批准号:19590426
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.91万
-
财政年份:2007
-
负责人:KAMEI Kaeko
-
依托单位:
Mechanism of interaction between tissue factor pethway inhibitor and heparin
-
批准号:11680605
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:1999
-
负责人:KAMEI Kaeko
-
依托单位:
海外基金