Critical role of hypothalamic dopamine in regulation of food intake by growing chickens on lysine-free diet

下丘脑多巴胺在无赖氨酸饮食生长鸡的食物摄入调节中的关键作用

• 批准号: 22580304
• 负责人: SUGAHARA Kunio
• 金额: $ 2.91万
• 依托单位: Utsunomiya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22580304/
• 关键词: 栄養・飼養; 摂食量; 視床下部; モノアミン; 脳微小透析法; リジン欠乏; ドーパミン; 鶏ヒナ; 血漿アミノ酸濃度; food intake; hypothalamus; monoamines; brain microdyalysis; chicken; brain microdialysis

1.Central perfusion of L-DOPA as well as peripheral administration of lysine kept the extracellularDA level in the VMH at baseline of chickens fed on a lysine-free diet.2. Keeping the extracellular DA level in the VMH prevents chickens on the lysine-free diet prevented from decreasing their voluntary food intake.3. DA in the VMH plays a critical role in food intake regulation in chickens fed on a lysine-free diet.

1. L-DOPA的中枢灌注和赖氨酸的外周给药使VMH中的细胞外DA水平保持在无赖氨酸饲料饲养的鸡的基线水平.保持VMH中细胞外DA水平可防止无赖氨酸日粮的鸡减少其自主摄食量. VMH中的DA在无赖氨酸饮食饲养的鸡的摄食调节中起着关键作用。

项目成果

Regulation of voluntary food intake in chickens

鸡自愿采食量的调节

• 发表时间: 2011
• 作者: 菅原邦生;ら;Kunio Sugahara
• 通讯作者: Kunio Sugahara

Voluntary food intake variation in growing chickens on lysine-free diet is attributed to the plasma lysine level

采用无赖氨酸饮食的生长鸡的自愿食物摄入量变化归因于血浆赖氨酸水平

• 发表时间: 2012
• 作者: Mohammad Rashedul Alam;FumiakiYoshizawa and Kunio Sugahara;Mohammad Rashedul Alam
• 通讯作者: Mohammad Rashedul Alam

Neuroendocrine regulation of sedation and excitation in neonatal chicks

新生雏鸡镇静和兴奋的神经内分泌调节

• 发表时间: 2012
• 作者: Alam M. Rashedul;Fumiaki Yoshizawa andKunio Sugahara;Takashi Bungo and Kunio Sugahara;Mitsuhiro Furuse
• 通讯作者: Mitsuhiro Furuse

Local administration of L-DOPA in the chicken ventromedial hypothalamus increases

局部给予左旋多巴可增加鸡腹内侧下丘脑的作用

• 发表时间: 2012
• 期刊: dopamine release in a dose-dependent manner Neuroscience Letters
• 作者: Mohammad Rashedul Alam;FumiakiYoshizawa;Kunio Sugahara
• 通讯作者: Kunio Sugahara

採卵鶏栄養における最新情報について

蛋鸡营养的最新信息

• 发表时间: 2010
• 期刊: 関東畜産学会報
• 作者: Mohammad Rashedul Alam;他;菅原邦生
• 通讯作者: 菅原邦生