Critical role of hypothalamic dopamine in regulation of food intake by growing chickens on lysine-free diet

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1.Central perfusion of L-DOPA as well as peripheral administration of lysine kept the extracellularDA level in the VMH at baseline of chickens fed on a lysine-free diet.2. Keeping the extracellular DA level in the VMH prevents chickens on the lysine-free diet prevented from decreasing their voluntary food intake.3. DA in the VMH plays a critical role in food intake regulation in chickens fed on a lysine-free diet.